List of drugs according to their
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TOXYLACT ENGLISH VERSION
ATC drug classification
System for Medicinal Products
ATC drug classification is used in
many countries to label and study
Each code contains 7 characters
denoting 5 levels of
The first level, the first sign, is a Latin
spelling letter denoting the anatomical area,
the diseased organ, which is treated with the
given medicinal products - this is the main
The second level, second and third sign, are
Arabic numerals - the main therapeutic group.
The third level, the fourth character, is
also a Latin spelling letter - the therapeutic
The fourth level, the fifth sign, indicates
the chemical group of the medicinal product.
Level 5, sixth and seventh characters are
again Arabic numerals denoting the name of the
active ingredient of the medicinal product or
combination of medicinal products.
Toxicological risk during
Toxicological lactation category I - the drug
and / or its metabolites are either not
eliminated through breast milk or are not toxic
to the newborn and can not lead to the
development of absolutely no toxic reactions and
adverse health effects in the short and long
term. Breast-feeding does not need to be stopped
when taking this medicine, which falls into this
toxicological category of lactation.
Toxicological lactation category II - the
drug and its metabolites are eliminated through
breast milk, but the plasma: milk ratio is very
low and / or the amount released can not
generate toxic reactions in the newborn for
various reasons, including degradation of the
drug in the acidic pool of the stomach. the
newborn. Breast-feeding does not need to be
stopped while taking the medicine.
Toxicological lactation category III - the
drug and / or its metabolites generate plasma
concentrations equal to or higher in breast milk
and therefore the development of toxic reactions
in the neonate can be expected. Breast-feeding
should be discontinued for the period
corresponding to complete elimination of the
drug or its metabolites from maternal plasma.
Toxicological lactation category IV - the
drug and / or its metabolites generate a plasma:
milk ratio of 1: 1 or higher and / or have a
highly toxic profile for both mother and
newborn, therefore their use is incompatible
with breastfeeding and it should discontinue
completely, not just for the duration of the
drug, or seek a less toxic therapeutic
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TOXYLACT is a toxycology data base.